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  • Jesse John Francis Clark

The Importance of Vitamin C

Thank you. Welcome. And thank you for your your warm welcome. Very nice to be in Sweden and your beautiful city of Stockholm. And talking about vitamin C is so it's an interest of mine. The Vitamin C, you many of you may know that my my primary interest is in the topic of vaccination. However, in the study of vaccination, what I have realized along the way is that much of what I learned in my medical education was lacking in details on how to support the biology of the human being. Mostly it was designed to suppress symptoms and to drugs that start with anti. So that tells me a lot. Now these drugs, as you know, they work very well that we can use in allopathic medicine. And when somebody is dying, they can come in very handy. But when people are just a little bit sick or when they are healthy, as you know, it can be very helpful to support the chemistry of the body using the design that it was designed in the earth, products that that were put here for us and not the products necessarily that the drug companies have made for us. So since I have learned to use vitamin C, I found that not only has my own health become extraordinarily better, but my prescription writing has gone down significantly. And the health of my patients has also improved greatly because vitamin C does so many things from the time that we are conceived, actually, until the time we die. Vitamin C is necessary for so many processes. I heard that many of you are aware of the molecular doctors here. Yes. Or several. Anybody or some molecular doctors. Yeah. Okay. So I don't have to tell you too much about the benefit of vitamin C, but I hope you will at least learn some maybe some more details to fill in the physiology of Vitamin C. And I will present to you some of the current research that supports the use of vitamin C, even in the sickest patients that are in intensive care units. This just came out this year in 2014. And then in the end, I will take questions and I will ask that if you can just write your questions down for now rather than stopping me unless I say something you don't understand, put your hand up and we will clarify for you if it's a word translation that you need.

Okay. All right. So there is a lot of mythology in the conventional medical realm that that trickles down and moves into society. And this mythology is mythology that I used to believe, and that is that vitamin C is used. It's necessary to prevent scurvy, but it doesn't really necessary to be given in any higher doses than we get in our food necessarily today. Well, I found this not to be true, not only for my patients and for myself, but the medical literature and some alternative literature really supports that. These myths are actually not true. One of the myths that you'll hear often from conventional doctors is that doses over 1000 milligrams are dangerous and wasteful and just gives you expensive urine. We hear that the body becomes saturated if you take 150 milligrams. So no use taking anymore. We hear that kidney stones can be a big problem and we have to be on the alert not to develop kidney stones. We hear that there is no science behind high ascorbate use, despite the fact that Nobel Prize winning scientists have shown that there is science and there is ongoing science for the use. We hear often that natural whole vitamin C is always the best thing to be used. Now food is always the best thing to be used first, but when you are really very sick, you will not get enough vitamin C from your food. Okay, I'm here seeing not so. And the other thing is that we can get diarrhea from high doses of ascorbate and we hear that this is dangerous and we can kill little babies and cause bowel necrosis. None of this is true. None of this has ever been proven clinically or scientifically. We also hear that you can get enough from food when you are very ill, and that also is not true. So animals use for sequential liver enzymes to convert glucose. Yes. It's very simple, actually, from into another chemical which has this fancy name right there and it is called Two Kito L Gula. No lactose. You don't need to know that. But. But then that shape shifts automatically into el ascorbic acid. And this is the magic chemical that has so many functions in our body that enhance our health and can be very life saving in certain situations and can be consumed very rapidly during illness. This enzyme right here, number four, is missing from human beings and some other animals, some bats, some guinea pigs and some primates. The gene that codes for it is present in humans, but it just doesn't work. We don't know why. So human beings and these other animals are dependent upon the food source in order to have this life saving nutrient. So let's take a look now at animals that make their own vitamin C. If we look at a cow, a cow will make 18 milligrams per kilogram per day and they will take in a total of around 12,000 milligrams plus all that they're getting around here as well. Okay. So he's making 12,000 or she and also eating the grass and the greens, which have more vitamin C. Then we can look at cats. They make their own 20 to 40 milligrams per kilogram per day for a total of around 180 milligrams per day intake. I'm sorry. Production. Now, mind you, the recommended dietary allowance for me is half of that about. Okay. All right. So now let's look at animals that are dependent upon the environment for vitamin C because they cannot manufacture their own. If we look at a wild gorilla, we'll eat approximately 30 milligrams per kilogram per day for around 4500 milligrams. If we look at the guinea pig, the classic animal that does not make vitamin C, which I believe is why this makes actually a good lab animal just to do research, looking for illnesses in humans is because they also don't make their own vitamin C and they'll take about 30 milligrams per day and again about 33 milligrams per kilogram per day. So it's my belief that this is actually a good place to start in estimating what our baseline requirements are even as human beings. 30 milligrams per kilogram per day, approximately. Now, this is me on a farm in New Zealand with two goats, the baby and the mother. And I found out interesting information about goats. And that is that when goats are healthy, they make 185 milligrams per kilogram per day, and when they are stressed, they can make up to 1400 milligrams per kilogram gram per day for a total of around 100,000 milligrams.

Okay. And one day the veterinarian came out to the farm to deal with some problems with other animals, and he volunteered to us that goats hardly ever get sick. And when they do get sick, it's usually something so bad that it kills them. So that is, I think, very interesting anecdotal information. Now, I make none of my own vitamin C and I am told that I only need 75 milligrams per day and that's about 1.2 milligram per kilogram per day. So as you can see, there's something very wrong with the estimation that we as human beings need, even when we compare ourselves to animals who make their own animals who are dependent. It's a gross underestimation of our actual need. There were problems with how these estimates for human beings were made, and I don't really have time to get into that. But briefly, it was done just on a few healthy men and women, very small group, and they looked at the wrong kind of cells in order to make this estimation of what we need. So the science behind this estimate is flawed. And some scientists came along later and said no, 200 milligrams per day and the authorities rejected that, even 200. So they still say 75 to 94, 90 for man, 75 for woman. And if I'm a smoker, they say add 35 milligrams. Well, I'll tell you that one cigarette uses 25 milligrams of vitamin C so you can see if I'm smoking ten cigarettes per day, I'm already tapping into my reserves of vitamin C. Okay. So I just want to emphasize that simply preventing scurvy is not the same as promoting optimal health. These levels here that they're. Telling us is for preventing scurvy. And they're still rather inaccurate because if one is to develop, say, influenza or whooping cough, these reserves can be depleted, depleted very rapidly. Okay. So I looked around to see if anybody studied the levels in the blood of vitamin C in people and what it is. And I found this study from Canada, and they looked at people who were coming in and out of hospital to have their blood drawn. So, they might be a little bit sick because they're probably, you know, getting blood tests. But this was what they found is that 84% they said was normal, this 23%, they said, subnormal, and only 11.4% they called deficient. Now what they call normal? I don't call normal because they're calling less that greater than 28.4 normal. I believe that 100 to 125 is probably closer to normal, and I'll show you why in a minute. So I think more than these feet, more than this is actually walking around with low levels. But let's look at the difference now in patients who are in hospital and ill. What we find is that there's much more of them that are subnormal 60%, subnormal 19% are called deficient, which is very, very low level here, 11.4 micro mmol per liter and only 21% considered normal by their very low standards. And if we look at this this graph at the bottom, what it shows that the hospitalized patients are the black bars and the outpatients are the clear bars. And you can see expect some overlap. But what I want to point out is that both of these groups had some people that were up around 100 or 125. And this, in addition to other literature that I have read and the dynamics of vitamin C in the body is what leads me to say I believe this is a better range for us to live in 100, 125, even 150 is easily possible with repeated either a high diet with this with this nutrient or with repeated doses of various forms. So this study concluded and said that nearly one in five had plasma vitamin C concentration consistent with scurvy. And even more disturbing to me was that 24% of these people, when they went into hospital, were taking vitamins and doctors discontinued most of it when they were admitted to hospital. So I wondered to myself now, if conventional doctors even knew about this, if they would do anything about it, because we still are living with this myth that we don't need to look at vitamin C levels in sick people and we don't need to supplement, although that is changing. But there was a doctor even back as far as 1950s, who had a rather interesting comment to make about his colleagues. This is Dr. Frederick Planner, who was one of the pioneers of using high doses of Ascorbate, and he cured many of the most atrocious diseases in the 1950s, including polio. And this black widow spider Black Widow Spider bite, which he gives a detailed case history. And in this case history, he's he says that there are some physicians who would stand by and watch the patient die rather than use this vitamin C, because they're still thinking that it exists only as a vitamin and it is much more than a vitamin. And I'll tell you more about that in a moment.

So there's another interesting study here, because it basically just works with food, with some kiwi fruits. And this is a study from New Zealand and they got some adult males around 30 years old, healthy, and they wanted to see what the vitamin C levels in the muscle were. So they volunteered for this horrible muscle biopsies. But we got some interesting information. They started by just measuring their levels, their blood levels, and they found that they're pretty much on the low end of normal. 30 to 40 was their range when they started. Then they said, just consume a diet low in vitamin C and stop supplements. And look, it dropped down within five weeks, dropped down almost to levels of scurvy. And then they said to half of them, have you take one half of a kiwifruit per day and the other half eat two kiwi fruits per day, and then we'll see what happens to your levels. And interestingly is that they were able to rise these levels fairly high just with two Kiwi fruits per day up to 70, and even the half kiwifruit had a pretty good effect in the muscle. Okay, now, mind you, different parts of our bodies need different amounts of vitamin C, the adrenal gland and the eye need very high. And. Ounce, for instance, muscle somewhere in between. So this is just an interesting study that shows you that if we did eat a minimum of five fruits and vegetables per day, that has vitamin C in it, that most of us could have pretty good levels. Assuming they're not sprayed with pesticides and they're fairly fresh and we're not smoking and being exposed to dangerous chemicals. So you can divide the need for vitamin C into two categories, and it can be the everyday needs, like detoxifying chemicals, like car fumes, like preventing damage from environmental sprays or from any poison because vitamin C acts as an electron donor. And what that those electrons does is fix the damage that's done by these oxidative stress. And I'll give you more detail about that in a moment. So that's why vitamin C is called antioxidant. So it can protect people from pollen and allergies also by acting as an antihistamine. This is very well-established in conventional medical literature that high histamine levels equals usually almost always low vitamin C levels when you give vitamin C histamine drops. I found clinical practice and evidence in medical literature that in instances where there's allergic reactions and histamine, vitamin C is very, very valuable and does not have the side effects as most conventional antihistamines have. It is also a cofactor for many enzymes, some of them that may collagen that make neurotransmitters, hormones and this carnitine molecule which we need in order to make use of fat that we eat. There are two medical issues that fill most doctor's offices, whether you're an alternative medical doctor or conventional medical doctor. And these two medical illnesses filled my office almost exclusively. And those were diabetes and high blood pressure. Okay. And both of them are associated with low vitamin C, and both of them respond to various degrees depending on the person and the dose of vitamin C, but respond well to supplementation. Both types of diabetes are becoming worldwide problems, epidemics. And both of them are largely preventable. And we also know that diabetics have lower vitamin C levels than non-diabetic about 30% lower. Even if you're a very well-controlled diabetic, diabetes is an inflammatory state. So we find that just about every aspect of glycemic control is improved with supplementation, with vitamin C. Okay. Heart disease is the other one. Now, heart disease is another problem. It's caused by too much oxidative stress, toxin exposure, toxins, both from inside the body and from outside the body. It's an inflammatory state. And when it affects the heart, it's basically one area in the heart that becomes really sick. But it's happening usually in the entire body. And again, every risk factor for heart disease is amenable, meaning improved by vitamin C.

So we know that blood vessel health is improved because blood vessels are like layers of bricks and mortar. And you cannot make that mortar without having adequate amounts of vitamin C, and you can have just an area in your heart that has scurvy. Even though your blood levels may be normal. And we know this from a biopsies that were done in the 1950s where they looked at these people who had heart attacks and strokes, that they find parts of the brain and the heart that are extremely low are vitamin C, and they're usually parts that have a lot of stress acting on them. Cholesterol and high blood pressure, all of these things are improved. There's adequate literature for you to look at. The physiology is known about how the vitamin C works. And so really the only thing that there hasn't been a whole lot of research on is exact dose. But when it comes to vitamin C, I believe that most people have to figure out what their own dose is. That is not the kind of thing that I can say. Every person with high blood pressure should take X amount of vitamin C because we all have different deficiencies and changes throughout time. Here is a book if you want to learn more about the heart aspect and the blood vessel aspect of vitamin C. This is written by a doctor named Thomas Levy. He is a cardiologist and he is also an attorney. And his viewpoints are very well backed by scientific literature. He has, in this one, I think, over 650 scientific references. And so it's a very valuable book that describes exactly how these changes in the heart and the blood vessels are affected by vitamin C and why? Well, here's how the damage happens. This is this imagine this is a cell of the body and this is the nucleus. And this is the nucleus here, sorry, with the DNA. And here is the mitochondria, which makes energy for the body. And so we have all these things with squiggly lines that are coming in and bumping electrons out of the way. Okay. We're made of energy, basically. Our bodies are made of energy that has basically electrons, protons, neutrons. And it's just the arrangement of these things that dictates the chemicals and the function. Okay. So if you knock an electron out of its place in the body, it's kind of like playing ever playing musical chairs where. Yeah, so, so there's one that's missing. So everybody's fighting for the last one. And that's exactly what happens with oxidative stress. Like, if I were to take the scarf from that lady in the front row and the person next and next to her where it is was to take I'm sorry if he was to take the scarf from her. She's without the scarf and the next person would take it from him and the damage would just keep going, as if having the scarf was the good thing. Not having the scarf is the is the oxidative stress. So everybody's competing to get that scarf that has been knocked away. Well, that's what happens. It's like a chain reaction in the body. If an electron gets bumped away, the molecule that's missing, that electron will always be searching for it. Another one. And when it finds it from another one, that one will go looking for another one. Vitamin C can. Stop this chain reaction and it can also improve the damage that has already been done by this chain reaction. So classic chain reaction is electromagnetic energy from the sun can bump this electron away. Then we've got the inflammation from microbes that basically when your immune system attacks them, is one way that we can have the stress. And also these microbes, they secrete toxin often like think of rheumatic fever and think of meningitis. These are both examples of viruses and bacteria secreting toxin. So they will also cause oxidative stress, even emotional stress. If I were in a car accident, the stress that that imposes upon me, even if I have no infection, is the same as far as oxidation, as all these other things. Emotional stress, physical stress, all impacts similarly. So we have also chemicals. Then we have antioxidants from food that can kick in, that can help. Drugs, pharmaceutical drugs are some of the worst culprits of oxidative stress. And then just our regular eating. So having some oxidative stress is you will always have. But we have built in mechanisms to deal with that. It's only a problem when you're built in mechanisms and your food isn't supplying the electrons that you need to help with this damage that's been done. So the damage can damage proteins. It can damage mitochondria. And it can damage DNA in the cell. It can damage the outside of the cell and can be a big problem.

So overproduction of these free radicals, free radicals is something that's missing an electron. It can cause damage to the nerves, to the proteins, to the DNA, the mitochondria and the fat, the lipids. And it can lead to all these diseases that we commonly hear about atherosclerosis, cancer, diabetes, rheumatoid arthritis, heart disease, chronic inflammation, strokes, septic shock. And this is just naming a few. So vitamin C can help with all these different diseases. There are two groups of antioxidants. Some acts as enzymes. And you've probably heard of glutathione oxidase. You've heard of glutathione own. Others are non enzymatic and vitamin C is called a non enzymatic and vitamin E is also non enzymatic electron donor lipoic acid and things like that. You can get these from food. So these all help dampen down the inflammation that's caused by oxidative stress. Mm hmm. So while vitamin C can prevent the damage by interrupting the chain reactions, these flavonoids, which is part of what you get in food in the whole vitamin C, these flavonoids will they will kill late out metals and toxins. And so that makes the vitamin C have a more powerful effect. So most people know the term oxidative stress. They've heard of it, they've heard of free radicals. But very few people can actually explain it. And and I can take some time to do that, and I'll go fairly fast, because most people find this part to be a little tedious. But I think it's necessary. Just to give you a little understanding of what this oxidative stress is and how vitamin C helps with it. So this is a mini version of the periodic table of the elements. Okay. And let's just think of water. To start with, water is two hydrogens and one oxygen. Right. And so what happens is oxygen has six electrons in the outside, their shells. Okay. If you know chemistry, you know this already. But but all elements have electrons in these shells that circulate around the outside. This outer ring likes to have pairs. None of them be unpaired. So oxygen has two that are paired, two that are paired, one that is not paired, one that is not paired. So it's the perfect marriage to have two hydrogens and one oxygen. When you have that, you have satisfied your hydrogens because hydrogens wants to on the outside they want to be paired and oxygens. These ones want to be paired. So it works out perfectly. They pair up like that. They share this electron. Everybody's paired up and happy and nobody can do any damage. Right? And because of that, water is very strong. Like a bug could walk on top of this water because this charge and how things line up is so strong. Well, here's water, but it's missing something. This one has had say maybe a toxin come along or sun come along and bumped the hydrogen off. So now instead. Of having water, which would be H2O. This electron and this H is gone. This is one of the most damaging free radicals that exists. It's called hydroxyl radical. So instead of being a safe, valuable molecule called water, it's dangerous. So now it has to find hydrogen from somewhere. And it's going to start a chain reaction unless something comes in and satisfies this need as soon as possible. And that's basically what an antioxidant does. Is an antioxidant is something that has extra electrons can donate them without itself becoming stingy and trying to steal. So here we have our hydroxyl radical, the dangerous one. But then if we just bring this hydrogen and that electron in, we're happy. Now we have water. Okay, so that's the basis. So instead of bringing a hydrogen from. Oh, sorry, we can bring hydrogen from many different things. Vitamin E can donate a hydrogen. You can donate. You can generate new ones in the body through glutathione. But we can also freely and easily bring these antioxidants into the body through vitamin C. And vitamin C is the most powerful antioxidant there is. We make many other ones in the body, but this one has more power.

So this is ascorbic acid. It's very bitter. It's the it's what we find actually in the natural food. But the the body likes to bring in sodium ascorbate. So our intestines need sodium to bring the ascorbate into the body so we can either take it as ascorbic acid and we will use the sodium from somewhere, something we've eaten. Or we can take this as sodium ascorbate where this would be sodium instead of this hydrogen, and then we would just have this one electron to donate instead of to. But if you take ascorbic acid, you have to to donate. So it's twice as powerful. So the ascorbic acid in food is actually quite powerful because it has two electrons to donate. Sodium ascorbate has one, but it's still very powerful. And this is what happens after it's done its work. It looks like that. And this is something that does not cause any damage and it can now go on to be recycled in the body. There are various cells in the body that will take the used up, form a vitamin C and turn it back into the the vitamin C that can be used in other places. And there are some cells that only can take in the used up form. So it's a very good system. That means that if you have taken 300 milligrams, you've actually taken more than that when you consider that the body is going to recycle some of that. So some of the cells that recycle our nerve cells, red blood cells, the mitochondria, some bone cells, and it's a very useful process. But if too much of this DHEA is the is the used kind of vitamin C builds up, we just get rid of it in the urine. It's very simple. If we have too much, we either get rid of it in urine or we recycle it in the body.

So if there's serious oxidative stress, we'll have a high build up of the used kind. And that's not good. Now for pregnant women and babies, the concentration of vitamin C in the body is very important. And that's because we we cannot our cells cannot divide without vitamin C, we can't make skin. We can't make connective tissue. We can't make bone or cartilage without vitamin C. It's extremely important to a developing fetus and it's so important to the fetus that it will take whatever it needs from the mother, even if it means she becomes depleted of vitamin C. So the baby will have in the placenta, will have twice the amount, as the mother in general has in her blood. The cord will have twice the amount, the baby will have twice the amount. But the amniotic fluid that the baby is bathing in and is swallowing as it's making its intestines grow longer has three times the maternal amount. So it's extremely important that mothers are getting plenty of vitamin C in the diet. And there are many doctors that think that mothers should also be supplementing while they're pregnant. In addition to that, vaginal delivery and labor uses extraordinary amounts of vitamin C, and we find that the levels drop in the mother after the delivery. The birth is an extremely stressful process, but it's a necessary stressful process. Nature thought of everything. There's always backup plans and always plans to reverse oxidative and inflammation states when they occur. So this is a very interesting article, by the way. You'll see these numbers at the bottom of my slides. If you go to a website, public medcom p u b, m e d, dot CEO m and you put these numbers in, you'll either get the abstract or the full text of these articles that I'm talking about. Okay. So this was a very interesting article called The Stress of Being Born, on which I highly recommend reading only because it's just so fascinating. And I'm just taking a little piece of this to show you that this is this is catecholamine levels woman during delivery has you know moderately high catecholamine levels. This is a man who is exercising levels of catecholamine. This is a tumor called Fisher chromosome tumor. It's a very dangerous tumor. It causes dangerously high blood pressure, can cause strokes and has to be aggressively managed and sometimes removed. And just touching it upon removal can be life threatening because the levels of catecholamines are so high from this tumor. Okay, well, the baby, when it's born, is even higher than this tumor as far as catecholamines.

So these high catecholamines have a purpose. It stimulates and basically jumpstarts the immune system. It basically clears the lungs out of that fluid. Think about when you are stressed out, what happens to your mouth. It gets dry. Catecholamines will help dry all those mucous membranes so the baby's lungs can function normally. It also helps the baby deal with the low oxygen level, which all babies have when they're born normally. So this is a normal part of birth, but it's very inflammatory and there are ways to deal with this. Now, that's one of the reasons why Mother having a good level of vitamin C and a diet high in vitamin C is important. But there a problem that can happen if the baby's antioxidants aren't high enough. And that is this problem that we see here, which is jaundice of the newborn. We're told that 60 to 70% of babies today have this and it's treated like a disease. When from my research, I really believe that this is preventable. And from my discussions with women who have supplemented with vitamin C, I think it's it's in my anecdotal understanding, but there's actually research that supports this idea, and that is that bilirubin is second only to vitamin C and its power to be an antioxidant. Bilirubin is a very strong antioxidant. Now, if bilirubin levels are too high and the brain is open and albumin levels are low, you can have encephalitis. And that's the big concern about having babies have high bilirubin. But I'll tell you that babies can have encephalitis even with lower levels of bilirubin, and they cannot have encephalitis even with higher levels of bilirubin because it's much more complicated than just this tunnel vision that conventional medicine has. High bilirubin equals danger. It's not so simple, but let's look at the relationship between the baby's vitamin C level and the baby's bilirubin level. This study from 2000. Seven did that. And they just look, they didn't start an experiment. They just evaluated these levels. And so they found that these babies that had lower levels of bilirubin had higher levels of vitamin C, and they found that these babies that had higher levels of bilirubin had lower levels of vitamin C.

So something's going on here. My belief is that if the baby has high enough vitamin C, that bilirubin is not necessary and the reaction that is stimulated in that baby doesn't happen. Well, there was an I searched the literature because I thought somebody must have looked at this at some point. And there was an Italian article from 1957, which I had somebody translate for me and you can get this article here yourself and this Doctor Gabrielli, he got 89 pregnant women during their first trimester, and he gave them one gram of vitamin C every other day. And then he looked to see who had jaundice when the babies were born. And what he found is that 61% did not have jaundice. So it's completely the opposite of what we are thinking is normal today. Mild was 24%, moderate 3%. And in every experiment, there are going to be some people you just don't know what happened with. So to me, this is very interesting and shows me that women, I believe now pregnant women should be taking at least 500 milligrams of vitamin C per day. But I happen to know dozens of women now who have taken between 5006 thousand milligrams per day. And I know that Dr. Kleiner was giving much higher doses of that in pregnant women in the 1950s, and he was even giving a bolus dose at the time of delivery between 10,015 thousand in an injection. And all he had was good deliveries and no problems in his cohort of patients. And he's written about this. And again, this is all literature that you can find online. Well, because we have this problem of bilirubin in babies, the solution is to put these babies under a blue light or put them in the sun. And it does work. It does lower the bilirubin. But the question is, is this the best approach or is this just an approach like allopathy like to do, which is to get rid of the symptom even if the baby is less healthy in the end? Well, there's evidence to say that that's exactly what's happening, and that is that they looked at these babies at their antioxidant levels after being put in these blue lights. And while the bilirubin levels did go down, the albumin levels went down, too. And that's not good because you want bilirubin to be connected to albumin and that keeps it out of the brain. Okay. They also had lower glued if iron levels and it lowered their vitamin C level. So the question is, are we doing these babies in really any big favor by putting them under blue light just to satisfy the fear of the doctors who don't understand the physiology of hyper bilirubin? AMIA. That's for you to answer. Okay. Now, let's move on to other things that the vitamin C can do. This is this has to do with structure and integrity of the of the physical body and especially bones, which we cannot make without vitamin C. The eyes are very specialized organs that are extremely high. Levels of vitamin C are stored skin, tendons and ligaments. And then the blood vessels, which I talk to you about already, as you can see, the layers of cells that we have here. And if you look in there, you can see it's like bricks all lined up and it's the glue that holds these bricks together that can come undone in times of low vitamin C.

So when you hear somebody has an aneurysm, low vitamin C, when they look at these aneurysms, when you hear someone has a cholesterol plaque with inflammation, it's low vitamin C. So anything the splitting apart of these layers is what we call atherosclerosis or what we call aneurysm. So these are both these are both conditions that not only do we find focal areas that don't have enough vitamin C, but they can be improved by taking very high doses. So in brief, I'm just going to show you how this works as far as collagen, because it's very interesting. If anybody here knits or has ever been a spinner to spin threads, you know that you start out with the threads and then you have to spin the threads together to make it stronger. Well, collagen is the same. Okay, so here we make this collagen, but then we have to weave it together. And for each O8, you see, they're one molecule of vitamin C is used. So you can imagine enormous amounts of vitamin C are used in order to make collagen and then it's woven together like that. And then it's put there, put into even the big fibers. So this is just basically your raw your raw yarn and now you want to take the yarn and make something with it. And that's what's happening here, is this is basically what's happening with the knitting for the bone. And then in between these fibers is where all the minerals are deposited. So vitamin C actually stimulates collagen synthesis and is necessary later on in the process. In order to do that weaving. So you even if you have good minerals, even if you have good amounts of calcium and magnesium, if you don't have enough vitamin C, you won't be able to make bone or skin. Now, bone isn't just about vitamin C, it isn't just about calcium. And one of the other myths that is commonly propagated in America I don't know about here is that people need so much calcium. Children need calcium. Postmenopausal women need so much calcium. Well, what I found in my career was that we're not doing people any big favors by giving them all this calcium because it's going to places where you don't want it. It's going into the heart. It's going into blood vessels. It's depositing in brain. So what has to happen is lower amounts of calcium need to be taken into the body. And then the molecules that tell the calcium where to go and tell the minerals where to go have to be brought in as well. Then everything works beautifully, like it was designed. So we know we need vitamin C, but we also need vitamin D, obviously. And I know anyone living up in this area is well aware of the need for vitamin D. Vitamin K2 is is one of the two normal forms of of vitamin K that tells calcium where to go in the bone. Other B vitamins are also extremely important. Trace minerals have to be there in order to make strong bone. And so a good, healthy diet that keeps the the the easily maintains a neutral in the body is important.

So if I'm eating a diet that's full of say I'm living on bacon and soda or Coca Cola, I'm going to be generating a lot of acid in my body. And if I can't get rid of that acid through breathing or through urine, my bone will start to buffer it. Okay, so everyone's nodding. So we get that the diet is very important, a well-rounded diet. There's no there's never a time where I say there is a primal panacea and it is a supplement. It's not it's always there's always multifaceted approaches to staying healthy. So this is a short list of conditions that require vitamin C, that there is adequate medical literature to support. But my slides got a little too complicated when I started putting in all these numbers, so I'm just going to read them off for you for now is that I have a study later that's going to tell you more about this. But vitamin C is antiseptic, it's antibacterial. You can put it on skin infections. It will improve. You take it internally, it will improve. You can put it on your gums. If you have gum infections, it will improve. So it's it's directly kills bacteria and viruses as well. It's been shown to be helpful in conditions in intensive care units, severe infections and sepsis. We see people survival improved and we know exactly why, because this systemic inflammatory response is the biggest problem in sepsis and why the blood pressure drops and why the fluid comes in the lungs. It's helped enormously by vitamin C trauma surgery and burns. There's literature that shows that giving high doses of Vitamin C to burn victims lowers the amounts of fluid that they need, lowers the amounts of infections, secondary infections that they have, and is enormously helpful. The processing of normal toxins that are developed, that are made in the body every day. I talked about blood vessels. I talked about histamine. Whooping cough is the place that I use the most, vitamin C, because I find this is an illness that not only does the vaccine not work for that 86% of of. Cases of whooping cough are in fully vaccinated children, and many people catch their whooping cough from vaccinated children. So this is an illness that whether you're vaccinated or not occurs and there's antibiotics, do not change the cough, except often will make it worse because you're impairing the immunity and doctors have nothing to offer. And so out of desperation, they offer antibiotics, which tends to make everything get worse. And parents will call me and say, I didn't want to take the antibiotic, but I did, and now my child is worse. What can I do? And so we start them on very high doses of vitamin C, even little babies. I've treated two week old baby with vitamin C, that baby is now one year and a half old. He's perfectly healthy and happy. So I've treated 64 year old people with vitamin C for whooping cough.

So every age group needs it with whooping cough because whooping cough is a toxin producing bacteria. And any any illness that makes a toxin needs to be neutralized. The toxin creates oxidative stress, which is an electron thief, and vitamin C gives it back. Also, it strengthens the lungs, it strengthens the fibers in the eye so that people that are coughing don't get these hemorrhages in the eyes. And I have never had a secondary infection in any of my babies or children that have been treated with vitamin C people. Mothers always say, but I heard about the secondary infection. I just say, I have not seen it. I know I've read about it in literature. I hear about it in kids who are given antibiotics. I have not seen secondary infections in my patients. You need enormous amounts. People get very nervous with the amounts of vitamin C that are required in these babies. But if you were to check the blood levels in these babies, you would see that even giving these very high doses is not raising their blood levels significantly because the toxin is is consuming the vitamin C very, very rapidly. Okay. Vaccine reactions. This can also be very helpful because a vaccine reactions are often in all vaccines cause inflammation. And whether you love vaccines or not, you have to admit that it's part and parcel with vaccination inflammation. So fevers happen after vaccines. The arms are often sore. It's undeniable inflammatory response that is considered necessary. In addition to that, vaccines contain aluminum, and aluminum is highly toxic metal that, when injected into a muscle, is very inflammatory and problematic and produces a lot of oxidative stress. And so vitamin C is very helpful after vaccine reaction. All right. So let me just see what slide I'm on now because I think I'm going pretty fast. I am almost halfway done. It's 7:00. We could take a break now because I think I've talked rather fast and we could get into the clinical. Now, what's coming up now is I'm going to talk to you about some of the research that's been done recently and then the practical applications of what to buy, where to buy it, how much people need. So maybe we can have our break now and then come back. Okay. I'll start by saying I'm pleasantly surprised at the warm reception I've received here, and I thought I was coming to talk about vitamin C and I could not really talk much about my other medical heresy. But I would like to tell you how I got to where I am today. And because somebody requested that I give a little of my history of how I became the the how should I say out outside of the box doctor that I am today? I started just like most other doctors start, which was very idealistic. I wanted to be a doctor and go to medical school and help people. And so I went to university and I got my degree in physics. And then I worked in a biomedical laboratory for two years doing many experiments on animals. And then I decided that I wanted to work with people.

So I went to medical school and I graduated and had the happiest day of my life at my graduation from medical school. And then I went on to my residency where we study for three years. And at the end of that I started to see some problems, which was that I became a highly sophisticated technician to hunt down disease and write prescriptions for all of my problems that I found. And that was about all I knew how to do. And this felt problematic to me. So I went and decided to specialize and learn more and did two more years in kidneys, thinking that at least that these patients really needed the drugs and they really needed this specialty care. And I felt that I was doing a lot of harm to otherwise healthy patients by making them worry about things and have to have all these tests and all these vaccinations and all these drugs that I didn't really believe in. So I went into nephrology and I taught medical students. I taught residents and full doctors. And I was in academic situation first, was at a university setting for two years, and then I went ten years, partly academic and partly private practice up in Maine. And during that period, I became increasingly unhappy with the narrow window that I was expected to stay within as far as what I could recommend for my patients, because I started to understand about oxidative stress and I started to understand about vitamin D and vitamin C and nutrition and all these things. That, to me made much more sense to start with, but it was frowned upon and by my colleagues, although some people referred patients to me just because I had that view.

So it was very mixed. But there was a period in 2009 where several people came in after having swine flu vaccine and they had normally had normal kidneys. And then after the vaccine, they had no kidney function and they needed to have dialysis. And I tried to tell my colleagues, I think there's a problem here with this vaccine. And I was met with such huge resistance that the irony is that that is what landed me here today, that had they said what they say for every other drug, if I give a statin and there's kidney failure, I give an antibiotic, there's kidney failure. They say, oh, of course, it's the drug, it's kidney failure. We stop the drug. But when it came to vaccination, it was completely different. And I kept hearing these doctors say to me, no, it's not the vaccine. It can't be the vaccine. Vaccines are safe and effective and they're necessary. And you can give them to everybody, whether they have kidney failure or heart failure or sepsis, because the benefit outweighs the risk. And to me, it was completely, intuitively wrong. And so I started looking at my patients over time after they would have vaccination. And I asked every new patient I saw, when was your last vaccine? And at some point I started to see that there was some correlation between vaccination and development of a protein in the urine or worsening protein in the urine or high blood pressure or autoimmune diseases, sometimes new autoimmune diseases or worsening of old autoimmune diseases. And I was continually told not the vaccine shut up. And so I started to do more intensive research and I wanted to see the answers to these things I was being told, okay, so I was told smallpox was eradicated by vaccination. And I thought, well, I always believe that to be true. Remember, I, I worked in the conventional system. I was told all the same things these doctors were told. The only difference between them and me is that I went and looked for myself. And I found answers that that turned my world upside down, literally to the point that I was making $300,000 a year in my job and very happy to the point where I said I was so alarmed at what was happening, at what these doctors were doing and what they were continuing to believe, despite the evidence that I left and I walked away from all of it. And I do this now. I study 6 to 12 hours every day, seven days per week, doing this as these people I'm staying with can verify that it's what I just feel. I have to do it. And it's not work to me because it feels like something that I've just been called to do. And so this book came out of my research with Roman BASTIANICH. And what we discovered was that not only did vaccination not get rid of smallpox, but it did not get rid of polio. And we also wrote about measles and pertussis and whooping cough in there. And we found, much to the contrary, of what the public is always told, that the vaccinations are what decrease the death rate when in fact stopping smallpox vaccines stopped the death rates and the diseases. In a town called Leicester UK, which you can read about in the book, it's very interesting that smallpox could not have possibly been eradicated by vaccine because only 5 to 10% of the entire world was ever vaccinated. It was sanitation. So we have more to thank our plumbers for and our and our trash collectors for our good health than we do the medical system for vaccination. And we show that and we prove it in the book.

So that was the start of how I started looking at vaccination. And since then I've looked more intensely at the infant vaccination program. And that is even more frightening because we were vaccinating earlier these infants. We are giving them more vaccines. We're giving them aluminum, which is highly neurotoxic. And all the while we're seeing in the United States one in six children with chronic disability, one in 58 with autism. And we're told that it's environmental, but we don't know what in the environment. And any parent who watched their child go autistic knows it is not environmental. And there is plenty of science to the contrary that is is just environmental, that the environment is what's being injected around the cells of these babies bodies. That's the environment. So anyway, so this is what I do now is as full time research. I have a small private practice and I just go around talking to people who are interested to hear the problems with the conventional medical paradigm and vitamin C as well, and then vaccination. So that's the history. It's a little easier in the United States to be a doctor like me because there are more of us that have stepped out and disagreed with the, you know, the army of doctors that are doing the things they're doing. So I hope that there will be more doctors in the other parts of the world that can see that it can be harmful to your career to step out. But the reward of being able to sleep at night and knowing that so many people will benefit from what you've done, whether or not you're able to maintain your good standing is worth it. If you Google my name, you'll see that I am considered a crazy person in the United States, despite the fact that I have studied more about this subject than any of the people that are calling me crazy person, that my patients have done nothing but get better over time rather than get worse. So if that's what crazy doctors do, then I'm happy to be among the ranks of quackery. We do have a really interesting study that came out this year in 2014 and sepsis evidence for I.V. sodium ascorbate. Now, I'm often called by people that say, you know, my father is in hospital and my mother is in hospital. They're having this problem. And I want them to get vitamin C and they won't because they say it's dangerous or there's no evidence. And so I take this article and this is free. You can get this online. And I say, you need to bring this in, because if they can say that is no longer safe, then they're just making it up now. Because what they did was that this trial, as they had this was just a phase one trial and it called for a phase two trial when they got the results, which were very good. So they took patients with all these horrible diseases, underlying diseases like liver failure, kidney failure, lung failure, like total organ failure, cancer, bone marrow transplant, hepatitis, you know, the kind of liver failure that makes you bleed through the esophagus, all kinds of problems. And these patients all had severe infections. And what they wanted to know was, was it safe to give high dose or low dose vitamin C to these patients and what would be the outcome? Now, we're commonly told that if you have kidney failure, you cannot take vitamin C, but if you're dying of sepsis in a hospital, you have to look at it rationally, that if it can save the life, then you put them on dialysis for a while, you save their life, and then they will come off of dialysis. And that's essentially what happens when these patients get sepsis and kidney failure. Most of them come off of dialysis at some point. So give them the vitamin C and that's exactly what they found. This is one of the charts from the study.

So what they did is they gave one third of the patients no vitamin C, they gave one third of the patients 50 mg per kg within 24 hours intravenous. And they gave other one they call high ascorbate, which I don't really call high, but they did 200 milligrams per kg in 24 hours, which equaled around 14 grams in the day. Now, I would have probably given them 100 grams in a day, but it's a start. And and they had an interesting result. This is called a sofa score sequential organ failure assessment score. It takes into account the Glasgow coma scale, different vital signs and organ function and it's highly accurate indicator of death during critical illness. So if you have a high sofa score in first 48 hours of intensive care unit, then your mortality rate is at least 50%. Okay. So you really want this this score to be coming down very rapidly. And they admitted in this paper that all the things they've tried over the years have not really done very much for this. So they said, let's try the vitamin C. Well, you can see the placebo. They got no vitamin C, their sofa score rose very bad. The low dose you can see the sofa score went down significantly and the high dose went down even more significantly. And I would take an educated guess and say that if they got the the 100 gram dose that I would have given that we would have seen it even more come down more rapidly, especially if they gave it as quickly as possible on admission to the hospital. And so the conclusion of this paper says that no patient in the low or high dose ascorbic acid treatment arms suffered any identifiable adverse event. So we know it's safe because we are able give it. To give it to these gravely ill patients who would have otherwise had a very high mortality rate. And we know that a very sensitive indicator of death went down rapidly. That's extremely significant. And this should be enough to have a doctor in a hospital give intravenous vitamin C when it's required. If that doctor is afraid of being sued, all they have to do is show this evidence. Here it is. Hmm. There are other diseases that vitamin C has had powerful effects upon. And this is some of these are documented in books. Some of them are in medical literature. They're very easy to find. The evidence for polio was was Dr. Cleaner, who cured 100% of his polio patients by giving vitamin C. And when he announced this at an international doctors conference, not a word was spoken. He was basically completely ignored. I think they just didn't know what to do with him. Nobody believed it. And so nobody tried it because polio, remember, was a disease that was crippling children and could only be stopped by a vaccination, although it was actually a very low incidence disease compared to many of the diseases we see today and over the ages. Hepatitis is very helpful that vitamin C because and this has been shown for all kinds of hepatitis, because toxins build up, because the liver is a detoxifying organ. And if it's not working properly, the toxins build up greatly. And if you give vitamin C, the liver function improves greatly. Viral encephalitis, rheumatic fever, a mushroom poisoning was written by Doctor Cleaner as well. Ebola. You know, this is the big fear today. Well, I have an article here in my computer that shows the series of patients that were treated in Africa and they were treated with all different. But it was kind of almost seemed random how they decided what to do for each patient. But the ones that were given Vitamin C survived and they they did better. And it makes sense because Ebola is a hemorrhagic toxin producing virus. Okay, any hemorrhagic disease, think about it. It's little blood vessels breaking apart, causing hemorrhage. What? So it's scurvy. So you want to get vitamin C? So all this calling for vaccination, I predict, is going to be a disaster. And what should be done is that these people should be given hydration because that decreases mortality by 50% just by giving them intravenous fluids. And vitamin C colloidal silver has also been shown by the US government research that's published online to be toxic to Ebola virus. So we have several treatments, but when you hear the World Health Organization, they tell you that there's no treatment and it's highly deadly disease and we need this vaccine.

So tuberculosis, we have an article from 2013 that showed that that vitamin C is highly toxic to the tubercle tubercular bacillus and infectious mononucleosis. And there's many, many others. Dr. Levy also wrote a book called Primal Panacea that has over 300 references and whole sections on different diseases that have been treated with vitamin C. One of the things that Finland asked me to do was to do a talk on tetanus. And so I spent several months this summer preparing that, and I'm just pulling out one part of it for you to show you. And that is that there was a study done in Bangladesh by Dr. Jahan. And what they did is they got 117 human beings with tetanus. It's very usually very high mortality in Bangladesh. And they divided them into two groups. And they gave half of that. They gave all of them conventional treatment, just like you would do for anyone with tetanus. But half of them, they gave 1000 milligrams intravenously every day a vitamin C, and here's what we see. It didn't matter the size or the age. They gave everybody the same dose, unfortunately, because it was not in milligram per kg. Everybody just got 1000. So the children got relatively higher dose than the adults. And we'll see the results of this is that there's this is the vitamin C group. There were 31 children between 1 to 12 ages. They all recovered. None of them died in the no vitamin C group. There were 31 patients, eight recovered, 74.2% died. Now, if we look at the adults between 13 and 30 years, remember, these are bigger bodies. It's getting the same dose. We see 37% mortality in the vitamin C group, 67%. Mortality in the No vitamin C group. And to me, this is a no brainer that had they given a milligram per kg dosing high enough, I think they could have saved most, if not all of these people in the second row. So this is evidence that if anybody has a wound, even whether you think it could have tetanus or not, all wounds are susceptible to tetanus. And even if you're vaccinated, you can get tetanus. I have a stack of papers on children and adults who have developed severest forms of tetanus, even though they were fully and appropriately vaccinated, some of them over vaccinated, still developing tetanus. So every wound should be treated rapidly. And so far as cleaning it, letting it bleed, applying anti microbial like colloidal silver. I put vitamin C right on the wound and I start dosing with vitamin C right away because there's also an animal study that showed that at any stage that you give vitamin C to an animal, whether they have developed symptoms or whether they have not yet developed symptoms, that you decrease the mortality, the death rate to zero, whereas if you do no vitamin C, the mortality rate, they all will die. So right away I start dosing with vitamin C with any wound and I am very aggressive with cleaning it, getting rid of dead tissue and removing dirt. Okay. So that's very helpful. And anyone who is concerned about tetanus, whether you're vaccinated or not, okay, now it's a more practical aspect. The foods are always primary number one place to go for health. And you call this paprika? I believe we call them red pepper in the USA, but they are very high in vitamin C, 300 milligrams in one one fruit is very high. So I love them. So that's good. Parsley 133 mg in 100 grams. So between these two items, you can get a lot of vitamin C in one day and then you've got broccoli, Kiwi fruits. We already talked about 140 milligrams in two kiwi fruits and I think I could probably eat ten in one sitting, so that would be plenty for a day. And then we've got tomatoes and citrus fruits, berries. You eat a lot of berries up here, and that's probably one of the main sources of vitamin C that you're getting. And you can taste how tart the berries are, and that's ascorbic acid you're tasting in there. And it also has all these flavonoids that I talked about before that takes the metals out and preserves the vitamin C longer. So food is always really good to have, but if you're very sick, you would need to have fill this. You need to fill up, you know, several baskets of, you know, with this food and you could never eat enough when you're acutely ill. But I think juicing, you can get quite a good amount. But then you have the sugar to deal with in some cases, and sugar competes with vitamin C on the cell. So you want to have a low sugar, low carbohydrate intake when you're wanting to get a lot of vitamin C in the body. So these I talked about the flavonoids and and so you can add these things to your other vitamin C containing foods and together they will be synergistic and, you know, dark chocolate is that's the good news is that there's lots of good things about it. Bananas, all citrus berries, onions, parsley and all these teas.

So they all have these flavonoids which act synergistically with vitamin C. Now, there are some people that really don't want to give a vitamin C that was made by a pharmaceutical company. So they say to me, Can I just give something natural? We have all these natural forms like Camu, Camu and rose hips and nasralla, and my answer is sure. That will give you around 250 to 500 milligrams in one teaspoon. That's about 1/10 of what you will get by the synthetic form. So if you're just having a little mild illness and you only want to do natural, then food plus this. It may be enough, but if you want to treat whooping cough this you'll never do it with. This would be very, very difficult. I won't say never, but it'd be much more difficult. You probably would have to take the whole jar over two or three days. You need that much vitamin C when you're dealing with sepsis and whooping cough and these other more serious toxin producing illnesses. But there's nothing wrong with this and perfectly fine, too, to do this. The problem when they make these is that they never really tell you the especially with camu camu. It's always an estimate of how much vitamin C is in it. And they say that the flavonoids are in there, but when they actually go and check its various levels because it's it's been sitting as powder. So it's not the same as having your, you know, your fresh fruit. I like this company here for for the Nordic places because it ships all over the world. I heard and the prices are very reasonable for all their products. And these are two main the main synthetic vitamin C that has very high milligram dosing. And so I recommend that every house has both of these in it all the time. They also sell colloidal silver 500 parts per million, and I recommend that every house has that because when you need it, you want to have it and not have to wait two days while you're biting your fingernails, wondering if everything will be okay. So these are good to have for any illness. And. Whether it's external or internal, you will not regret having these items in your house. And if you have a friend or neighbor in need, you can help them also. Okay, so these are the synthetic forms we have here, intravenous. I personally do not give intravenous because I don't deal with cancer and these types of illnesses that require these very high bursts of of intravenous. But it can be very helpful in certain situations with Lyme disease, with serious heart disease and with cancers. Intravenous, in addition to these other forms, is very useful. Then this is sodium ascorbate and this is the light of phosphoric, and these are the two that I think every household should have. This is very good to give to babies because it's just easy to swab inside of the mouth and it gives them rapid absorption and high blood levels. It's also good to give to people who are very debilitated and ill because you can bring this into the body without using a lot of energy because it comes right into the body, like almost like a solvent comes in. Whereas this is very good. This is the kind I take because I'm cheap and this is much less expensive and I'm not acutely ill and I don't need to conserve energy. So this is what I take. It's what I give to my pets and my family because it's it's just very useful. And it also will give you a bowel flush. And sometimes that's a good thing to have. You know, when people are toxic, a lot of the toxin comes from the bowel and it's got to be detoxified by the liver. And if you can flush out the bowel just one time, I'm not talking about giving whole day of diarrhea. That's don't do that. But one my goal usually is to have somebody have to loose bowel movements per day. And then I feel that they have pretty much gotten as much as they can comfortably tolerate. And I'll talk more about those in a minute. But I like this form. You can brush your teeth with it. It will not cause any kind of erosion or enamel breakdown because it's buffered. Okay.

So it's also it's a little salty, but it's it's not so acidic that it's up that it will curl your hair. And then this is ascorbic palmitate and this is a molecule that is a half dissolves in fat and half dissolves non fat. And so theoretically should bring the vitamin C into the fatty compartments of your body. That's theoretically in real life, it has not been shown to be so impressive, but it's something that if you're doing a multi vitamin C protocol, you can add it's very expensive and it's not the way that you want to supplement on a regular basis. In my opinion, you just don't need to do that. And it's 500 milligrams in one pill, I think maybe 250, I can't remember. So when you need very high doses, you don't want to be taking ascorbic palmitate. All right, so let's get on to the question of do we just make expensive urine? And it's a complete waste of time to take high doses because this is something you will hear and people will be very emphatic and very certain about this. So you can take a picture here and show it to them. But this came from a conventional medical doctor, doctor living in the USA who's done a lot of the research in National Institutes of Health. And what they show is that if you take 100 milligrams, it's 80% bioavailable, so you'll absorb 80 milligrams. So low doses. When you have high need, you'll absorb a lot of it. If you take 1250 milligrams, it only becomes 46% bioavailable. So in a sense they're right because it's less bioavailable when you take more. But look, you're absorbing 575 milligrams, so you're still getting a much, much higher dose into your body, even though you're going to be relatively more spilling into the urine. But that's okay if you spill vitamin C into the urine because it's actually good for the bladder and actually can decrease urinary infections. And there's some evidence that it can decrease kidney stones. We'll get to the kidney stones in a minute. So don't worry about spilling urine, spilling vitamin C into the urine because it's it's healthy for the urinary tract. And you have to be smart about it if you're somebody that tends to form kidney stones. I'll talk about that in a moment. So that's the oral bioavailability. If you're giving intravenous, it's 100% bioavailable. So how long does it last in the body and how high of levels can we get here? We see this is one dose of 1250 milligrams sodium ascorbate. And this is 36 grams of oral of spirit. It's basically a whole box. It's a huge, enormous dose, which I do not recommend that you take. But this was done on human volunteers just to see how high could we get their blood levels. Because the NIH said that we really can only get the blood levels up around 70. Well, they were wrong. The NIA gave one dose and then they waited till here to check. When they didn't realize that even with a small dose, you're getting an increase in the level. And during that time, when you have an increase in the blood, all those organs that like to hold on to vitamin C will grab it before it goes out in the urine. So your scurvy in your heart has a chance to grab some of this vitamin C, while the levels are high, your eyes and your kidneys have a chance to grab it while the levels are high, and then it drops down. But and I measured it here and said, Oh, well, all we can get is 70. And that's all there is to it. And they measured white blood cells, which is unfair because white blood cells have pumps that hoard vitamin C. So it was unfair experiment to make these assumptions. So we now know that with just a small dose, we can get that level of 150. And if you have the flu or a cold, you can take another dose here and here, and you can continue to maintain that higher dose in your body. And if you.

So if you didn't take 36 packs of life as almost say you just took two or three at a time, you probably would be up around here and maintaining this. So that's what we can do with the oral vitamin C that we have at hand. And it's the most useful and it's what our bodies need most when we're in need of treatment for acute diseases or chronic diseases. I don't believe we need intravenous vitamin C for all but a few different illnesses. Now, remember before we were talking about a level of 400 for the kind you take by mouth. Now we're talking intravenous and we get levels up 15,000 or more with a with a dose of 100 grams times one. The problem is that you can see within 6 to 8 hours it's totally gone out of your body. And unlike oral vitamin C, where you can continue to take it, you can't go back and say, Hey, doc, can I have another? You mean you could, but you don't need to. So. So intravenous is useful because there are some cells that you really have to shock with the high levels of vitamin C, like cancer cells to kill them off. Cancer cells are different in that they don't have a certain enzyme that actually protects from the oxygen, from the oxidative potential of vitamin C, which is a whole other story I can't get into. But cancer cells are different and six cells are different and they are actually killed by these high levels. So that's why we need to have high levels during these periods. Also, high levels can get the the vitamin into the places where it normally wouldn't go. So it can be very useful to have intravenous, even six, even. What do we have here? This is ten grams will still give you a level of 6000. So in these intensive care patients, we could be maintaining them all day, you know, in a range right around here if we just kept the infusion going at a high enough rate, which is really what I would like to see those phase two studies do. Okay. So let me just get into basic recommendations. Okay.

So if you're taking sodium ascorbate, liposomal, vitamin C will not give you diarrhea unless you take a huge amount. So I've never induced diarrhea in anybody with liposomal, but with sodium ascorbate powder. The kind that I find most affordable and helpful is that it's good on a day when you're just home to assess what your own bowel tolerance is and make sure you've drink plenty of water before you start to do this because you want to have a good urine flow just in case you're one of these people that has a tendency to form kidney stones so that you don't find out on this day. So we take it if you're an adult, you can start by taking one or two grams every 2 hours. You could even go three or 4 hours and you just wait. You'll start to feel like a little rumbly feeling in your belly, and you may or may not develop diarrhea. Usually if you have the first sign is the rumbly feeling and then then write down how much your total was before that happened. And so if you want to supplement on a daily basis, say you have rheumatoid arthritis or you have a gum infection or something like that, then you can basically take somewhere around 50 to 90% of what gave you loose bowels, and then you can adjust the dose accordingly. I recommend taking it more than once per day. If you were to go ahead and take ten grams all at once, you're not going to maintain it in your system for very long. But if you take two or four or five grams, maybe two or three or four times. Was a day, you're going to hold on to more of it. So the circumstances vary. You know, we all can stop. We all will start at different levels of vitamin C in our body. We all will start at different levels of vitamin C deficiency in various organs. We all eat different food and we are all exposed to different things. So most of us will will fall within one range, but there will be people on the outside that will need different doses. So that's why I think people need to figure their individual ballpark dose. I usually take around maybe 2 to 4 grams on a regular day when I'm traveling and, you know, airplane flights and trains and, you know, doing talks like this, I find I can tolerate 20 to 20 to 30 grams in a day. And so it's really variable depending on the stress level. I remember stress can be emotional, psychological, physical toxin. Many ways to create the exact same phenomenon in the body. If you have a high carbohydrate intake, it'll make it seem as though you can't tolerate as much vitamin C. So remember that if one day you take it and you seem fine and the next day you take it and you have diarrhea, think back on what you ate during that period and you may get the answer. Also, having unhealthy bowel bacteria can make it seem like you can't tolerate as much. So it's always good. You know, all of my patients, the first thing I do is I deal with the bowel, the bowels of number one importance, because most of the time they have been insulted by numerous antibiotics and a terrible diet. And so the bowel always, number one, fermented foods, probiotics, and then vitamin C, and there's evidence that vitamin C actually actually feeds the healthy bacteria and kills the toxin producing bacteria. They actually use sodium ascorbate in the sausage industry just for that, because sausage is essentially fermented and it has can have E coli growing and they find that with sodium ascorbate, the fermenting bacteria thrive and the e coli go down in the cell. So if anyone's worried about killing off their healthy bacteria, it's just not what happens. Lactobacillus tends to to to thrive in the setting of ascorbate. Okay.

So in general, adults around 2 to 3 grams are tolerated very well without any adverse effects or diarrhea. Now there's always an exception, but probably everyone in this room can tolerate one gram in the morning, one gram in the evening. Okay, so what have other doctors over time recommended? And you're going to see the huge variability in what doctors have recommended because of our individuality and because of what these doctors were looking at. But Dr. Linus Pauling, who was the Nobel Prize scientist who really in our modern era anyway got the ball rolling as far as vitamin C and health and treating cancer. He recommended anywhere between 2.3 to 9 grams per day. Dr. Irwin Stone was another really important contributor to Vitamin C science and wrote a really great book that has a lot of the information on diabetes and other diseases. He's recently passed away, but the book is still available, I believe, at least in used form. It's great book to have on your shelf because it has a lot of medical references. So he said 70 milligrams per kilogram per day and that's about what a rodent would take. It would take in in a day or would synthesize in a day. Rather, Doctor Cleaner had the more specific guidelines. And he said, if you're a child, one gram per year of age, up to ten years and adults are ten grams per day. And these are people that were real hardcore believers in vitamin C. And then Dr. Steve Hickey, he's living and he's written some of the, I think, most important vitamin C literature. There's one book called Vitamin C, The Real Story that is fantastic and very useful. And there's another book as well that he wrote with Hilary Roberts, I believe. So these are really good resources that are available in electronic form and in hardback or paperback, rather. But he says and I kind of I kind of align more with with his dose recommendation, which he says somewhere between 500 milligrams to 20,000 milligrams, depending on many factors. And a lot of the research that showed the improvement in the status of heart arteries and cholesterol really only showed around 500 milligrams per day. Dr. Levy says 2000 milligrams a day. Is minimum of what you should have if you want to deal with atherosclerosis and these kinds of problems. But again, I think individual dosing really depends on a lot of factors that should be taken into account as well as your baseline status, your diet and your stress level. So my suggestions on daily use of sodium ascorbate is that if you're a healthy person and you're stress free and you have minimal toxin exposure and you eat a lot of organic fresh produce that you don't need a supplement at all. But hardly anybody falls into that category. And I mean, I fell into this category last summer when I was, you know, more relaxed and in a place where there was you know, there were trees and gardens everywhere. And we're able to get it right out of right off the plant. And it was fine because I was probably getting somewhere around 500 to 1000 of whole vitamin C just in the diet. And I didn't need very much. So if you have chronic illness, you'll need higher doses. Other indications for everyday use would be toxin exposure, radiation pollution, chemicals. Anyone who drinks more than I'd say one drink per day probably should be supplementing or heating a very high vitamin C diet. Smoking, drugs, constipation is, in my opinion, is a sign that there could be vitamin C deficiency, and it's always helped by vitamin C.

So people strive, you know, to get their kids to move their bowels and they try giving them prunes and they hate it and psyllium and all these things, which is fine. But add a little bit of vitamin C and see what happens is very effective. Again, travel I mentioned travel is is it just I it's very toxic to travel in many ways. And when I used to travel, I would almost always get sick and I would be sick for, you know, between three days and two weeks and sometimes would take me three weeks to get really normal again. And now I just feel a little bit of something coming on. And I take one pack of liposomal and several larger doses of sodium ascorbate and within hours the symptoms are gone and I don't get sick. And this happens over and over and over again. So I am testament to the good effects of vitamin C when traveling. I never travel without it. So this is the multi vitamin C protocol that Dr. Levy talks about in his book Death by Calcium, I believe, is where he mentioned this is a very good book. And so he talks about taking the liposomal, the multi sodium ascorbate. We've already talked about most of this, the ascorbic palmitate and the intravenous, and those are the benefits to each particular kind. We talked about how easy it is to bring in the liposomal into the body. We talked about the bowel decontamination with sodium ascorbate and the high, high levels. You can get both in the cell and outside of the cell with intravenous sodium ascorbate So a lot of people say, well, why not ester? See, because calcium is so good for me and Ester Si is buffered and that's what's on all the shelves. So it must be good. And, and I just hold my head and say, how can this be another area where everybody has the wrong information but it is the wrong information? Ester Si is calcium ascorbate most people in the world are taking in too much calcium and they're not taking in the elements that tell that calcium where to go. And that's the problem. It's not that we don't get enough calcium. So if you're sick and all you've got in the house is calcium ascorbate, then go ahead and take it. But if you want a daily supplement, this is not, in my opinion, what you should be doing every day taking in this calcium. I wrote to Dr. Levy and I asked him, well, what about growing kids and babies? And he said that nobody needs more than 400 milligrams a day unless you're lactating. Woman I think there's one other stipulation or last trimester of pregnancy, you would need twice that. So if you're going to take ecstasy and you need a four gram dose, let's say, then you're going to be getting 400 milligrams just in that one dose I mentioned before that in order to bring the vitamin C into the body, that you need to have the sodium because the transporter, it's like a little wheel is how they basically show it and you have to bring it to sodium with each ascorbate. And so it's physiologic, it's what the body wants is the sodium with it. And people say, well, we love ecstasy because it's buffered. Well, the of sodium ascorbate is around seven so it's buffered to your 7.4. So it's not that far different. From your own age, this is less of a problem. But in order to make the ecstasy requires high heat. And you can make the you know, the used up portion will be higher in the supplement. So this information is available on Dr. Levy's book, Death by Calcium and this paper by Dr. Sealy from 1991. Mm hmm. Also, they those were used together with Dr. Levy's writing. So true. Calcium requirements. This is right from Dr. Levy's book, Age 0 to 15. No more than 400 milligrams per day, age 15 to 35, 325 milligrams. And then so on older 220, 170. And then the exceptions are the women in last trimester and lactating women. Because, you know, obviously, the growing fetus is taking not only the vitamin C, but the calcium and the milk is some calcium is leaving as well. So the mother is going to be depleted if she's not taking in something. This is an interesting paper by Dr. Sealy from 1991, and it just showed that the death from heart disease and milk protein consumption that did not include cheese, it was basically, I guess, milk and cream. And they looked at the male. These were old the older males, the younger males. They looked at two and had the same trend. But you can see that Finland has this is a rate per 100,000 deaths and milk intake. And you can see that Japan did the best because they don't drink. They at least then were not drinking very much milk and had a low heart death rate in their men. You can see Sweden is higher and Finland is even higher and USA was down here. It's still all very high compared to this lower group here. And it's probably not just the milk, it's probably not just that because these cultures and their diets are all different, but it's something to think about in terms of that. We know that high calcium diets don't go into the bone necessarily. Okay.

So safety and I think this is probably a very strong argument in favor of vitamin C, yet we hear constantly over and over and over that vitamin C treatment is quackery and that it's potentially dangerous. And I've been attacked publicly online and for my writing about this, saying that I am putting the public health at risk by recommending vitamin C. And my answer to that is that there are no reports of healthy people overdosing or dying on vitamin C and that 227 gram ingestion in an adult would survive per the pharmacology literature. Now let's go over to the common over-the-counter drugs and have a look. The things that these same people that are accusing me of causing public health problems are prescribing like candy to everybody. We see 3 to 28% of hospitalizations per year due to adverse drug events. In USA. We see 0.31% of them die. 380 people per day are dying in the United States because of over-the-counter drug ingestion. Paracetamol is something you're all well familiar with. It's something that's said to be good for everybody and should be used for fever treatment. My opinion is that fever treatment should never be treated with something that just lowers the fever. You're completely going against nature's most valuable mechanism to protect you. And you're, you know, basically shooting the attack dog because it's barking. You don't want to do that.

So paracetamol in USA, 56,000 emergency room visits, 26,000 hospitalizations, 450 deaths per year from an unintentional overdose. Then we have these non-steroidal anti-inflammatory agents that are used in a lot of older people, and these people are developing ulcers, 41,000 hospitalizations per year and 350,000 days in hospital, 3300 deaths per year from these drugs. Now, the real irony, in my opinion, is that vitamin C is a helpful treatment for these ulcers, that it kills Helicobacter pylori and that it helps the new tissue grow. So not only are they are these people that are attacking the need and safety of vitamin C, putting their own patients at risk with these drugs, but they're overlooking a valuable intervention that can help with fevers in children because it fuels the immune system, it fuels the white blood cells to do the job they're trying to do when that fever calls them to work. So vitamin C is helpful for these problems. It actually helps reverse liver damage and prevent liver damage and detoxify the liver in the setting of cirrhosis. This is conventional medical literature right there. There's something called an LD 50, and that is the lethal dose, lethal dose required to kill half of the members of a tested population. So the higher your l.D. 50, the more safe your substance is and the lower your LDL 50, the less safe it is. So you can see this is the dose in milligrams per kg of wait and look we're aspirin falls 200 and look where paracetamol falls 1944 and look for vitamin C falls. Hey, the pharmacology is the pharmacology. So if you're met with this kind of uneducated resistance, these are the things to reply with. So it's generally accepted that the lethal dose for a human is 11.9 grams per kilogram, which would be about 755 grams of pure vitamin C taken all at once. If you want to kill yourself that way, it will not be very easy. Okay, so there are some conditions that we have to be thoughtful about in using vitamin C in high doses. Okay. One of them is called glucose six phosphate dehydrogenase deficiency. It's a rare disease. You're probably see very little of it here unless you have people that come from Mediterranean and African countries. It's an X-linked disease. So it's very rare in women. You'll see it in men more often. But still, when these people need vitamin C, you can give it to them because it's not going to accumulate in the body and cause problem because of this enzyme. Time deficiency. There's research that shows that when these people are sick, they can tolerate up to 6000 milligrams. But it's something if you're planning to give a very high dose of intravenous, they always check for this enzyme deficiency first and just a good idea to do. But when somebody is sick, you don't mess around. You just give them either the low dose or a moderate dose. There are other drugs that are commonly used in hospital every day, like sulfa drugs that can actually cause this problem. So when people say to me, Oh, you're putting your patients at risk by not checking this, when someone has the flu, I ask if they check for it when they're giving sulfa drugs to every woman with a urinary tract infection first. That usually ends the argument. But I wrote an article on this that you can read there, where I go into much more detail about this deficiency and there's a whole chart on the different drugs and foods like fava beans can actually cause this, you know, problems in these people. The blood cells can break open. That's the problem with this deficiency.

So something to think about. But when you need those, because there's an illness, it's not a big issue. Okay. So let's talk about kidney stones because I'm a nephrologist, I'm a kidney doctor. I see lots of kidney stones and I don't take them lightly. They're extraordinarily painful. Women who have had kidney stones and natural childbirth say they would rather have natural childbirth. So we don't want people to develop kidney stones. They can destroy the urinary system. It can cause kidney failure. And it's not a situation you want to provoke by any means. You'll find literature that says vitamin C does make stones, and you'll say, find literature that says it doesn't. I believe that there's more evidence and clinical proof that it doesn't than there is that it does. And I believe there are things we can do in people who tend to form stones to prevent this problem. But there are two studies done by this doctor here. One was in men and one was in women. Was a very large group of people. 85,000 people. It's a pretty good, big group. And they showed that there was lower stone risk in males that took around 1500 milligrams of vitamin C per day and that there was no increased risk in women who took doses like that. I've really combed through the medical literature looking at the stone literature because I thought, if this is a problem, I need to tell people to be careful. And what I find is that they're a rare case report that tells of a person that came into the hospital dehydrated. And then they give a history of taking vitamin C, then they do a biopsy of the kidney and they find oxalate. So I think this probably could happen. The question is, are these people have a primary disease that makes them make more oxalate, which can happen. But either way, you don't want it to happen. So if you're dehydrated, get hydrated first before you take a big dose of vitamin C unless you're in a life threatening situation. There's another study that does show an increased stone risk in older men. It was like 1.4 in the non vitamin C group and two point something and they said it was two fold higher, but they were still really low rates. And again, I think we can prevent this by certain very simple measures. And this was done actually at your Karolinska Institute in 2013, and it's a free paper that you can get online. So the problem is that three quarters of kidney stones are about three quarters, and sometimes it can be a little higher than that are made of calcium oxalate and this oxalate can form as a byproduct. It's one of the end products of vitamin D, vitamin C metabolism. And but there is a good study by Dr. Wenzel back in 1994, because before that there was a lot of hype about how this oxalate was forming huge amounts in people who were taking vitamin C. And so what this doctor noticed was that what was coming out in the urine was actually vitamin C, but it was turning into oxalate in the specimen dish. And it was it had to do with also how they were doing the analysis that it was turning to oxalate in that analysis. So he decided to give people doses up to ten grams per day and look to see if these people are making more oxalate in the urine or not. And he found that it was only about 1% of the urinary ascorbic acid turned to oxalate, and he said there is no genuine increase in urine oxalate despite a greatly increased ascorbate intake. Okay. There are many doctors that are stating the anti stone forming properties of vitamin C and Dr. Cathcart is one of them and he, he talks about that he started using vitamin C in very high doses, 200, 300 grams in people back in 1969. And he said later he read that ascorbate could cause kidney stones, but by then he already had all this clinical evidence that it didn't. And so he continued prescribing massive doses to his patients. And he said that by 2006, he put 25,000 patients on massive doses of vitamin C and none of them developed kidney stones. He said two of them went down on their doses to 500 milligrams and developed a kidney stone. But once he put their dose back up again, he had they had no more problems. He also added magnesium and vitamin B6 to their program and he said he thinks they developed the stones because their dose was actually too low. Ascorbate in the urine actually will bind calcium that can turn into calcium oxalate. So there may be a benefit of having it from that standpoint. High doses of very high doses of ascorbate is actually a bit of a diuretic and will increase the urinary flow. And remember, silt forms where there is not very much flow.

So if you have a high flow in a system with a lot of water, you'll know that crystals just do not form as easily. So you need concentration, you need the proper chemistry, and you need low flow to make these stones. Also ascorbate in the urine kills bacteria and for that reason the kind of stones that form in infected urine. There are some that they called Struve, right? That they can be limited by having Ascorbate in the urine. So they're actually benefits to having vitamin C if you're a stone former. But again, I believe that we have to be smart about it. And I say that there's caution warranted if you're dehydrated, if you have low urine flow. So I like to see the urine flow around in an adult, maybe at least one liter per day. Ideally, when you're doing a lot of vitamin C, maybe one and a half or two, if you have a known tendency to form stones, then again drink a lot of water first and continue drinking it while you're taking the vitamin C and you can even squeeze of lemon into the water, which gives you citrate. And citrate is a natural stone inhibitor. We use it. There's a urologist in the in the audience who confirm that we use this in drug form. Actually, sometimes it's very, very successful at stopping stone formation and stone formers, and you can get that just by squeezing a lemon. So we use that a lot in nephrology and urology. Instead of prescribing a drug, we just tell people, put half a lemon in a liter of water and that will help you. And we've actually seen of the urine go up that way. It's very, very effective preventing stones. If you have less than 20% of your what's called glomerular filtration, you want to be careful doesn't mean you can't take any vitamin C. It just means that if you're if you're sick and your body's going to use it, then maybe you can tolerate more. But you're still probably going to have higher oxalate levels if you're on dialysis. Probably just take a small dose before dialysis, let it do its work, and then the oxalate will be removed. If you have this enzyme deficiency again, if you're very sick, you can tolerate the vitamin C, but if you're not that, you have to be smart about it and don't go overboard. And then there's this disease called hemochromatosis, this hereditary form. And let me let me back off for a second and say that if you're iron deficient, there's a lot of evidence that if you take vitamin C with your iron, it changes the charge of the iron to make it very easy to absorb. So that's a good part about taking a vitamin C when you're iron deficient. But if you have too much iron in the body, there is a little bit of evidence that taking high doses of vitamin C can make that worse. But there's actually some evidence Dr. Cathcart talks about this, that people with this disease could actually be protected by taking the vitamin C. So everything isn't always so, you know, hammer and nail. So my advice is always it's just good to stay hydrated with good quality. You know, if you can have alkaline water, alkaline water, but if not just good quality, clean water all the time because our bodies are largely water. And so that's what we're made of. We want to have good water in the body and we want to keep the urine flow up high enough, especially if you're taking vitamin. Add the lemon to the water if you think you're have a tendency to form a stone or if you're dehydrated and you're concerned that that could be a problem, keep going with the lemon. Lemon is just so good for you in so many ways. Consider the real risk factor for kidney stones again. Allopathic medicine. Hammer nail, oxalate kidney stone. It's not that simple. People's diet has a huge impact on kidney stone formation. People who tend to drink lots of soda and eat junk food and have high fructose corn sirup and lots of sugar tend to form more stones. If there's a lack of citrate in the diet, citrate comes in your, you know, your citrus fruits is where you find a lot of it. And then the urine can be changed according to what kind of stone you make. But putting the lemon in the water is very, very helpful and staying hydrated. You know, there's a book called What's It Called? Your Body's Many Cries for Water. It's a really interesting book. They'll shaking their heads. It's, you know, water can cure so many of the problems that people go to doctors for, you know, headaches, even some ulcers. There are just so many things that water alone can do for you.

Okay. So here are some questions I think about. I think why are there so many? The majority of stone formers never take vitamin C, but we're just told over and over again who you know, that vitamin C is going to cause a kidney stone. Why is it so viciously scrutinized, given it has a very low toxicity profile and a huge benefit profile higher than any benefit I can think of of any any prescription drug or any over-the-counter drug. And what if all these patients that have benefited already, you know, the reporting clinic in USA is a conventional oncology clinic and they give chemotherapy there. And for years now they have been giving high doses of intravenous vitamin C on the on the every other day, you know, the days they're not getting chemotherapy. And there is an article in the Journal of Ortho Molecular Medicine from 2002 that I recommend you have a look at, because they talk about that they have used 194,000 grams of intravenous vitamin C administered to 275 patients with no sign of serious kidney disease or any other significant side effects over six years. Now, I've seen mention, you know, in these people that are dealing with really sick patients requiring high doses of vitamin C, if there is a problem and they have too much in their system, if the kidney starts to, you know, become sluggish, they give a big dose of intravenous fluid and a diuretic, and it just clears up the whole problem. So if a problem does occur, it's not like the end of the world. There are things that can be done. Well, this is my last slide. And I'm told this actually by people that are on my side. Often people write to me and they're, you know, they're into health and they understand that allopathic medicine is problematic. And they tell me that I'm actually giving bad advice because I'm telling people to take synthetic vitamin C, and I'm told that that it doesn't cure scurvy. And I at first I thought, oh, no, I hope I'm not telling people the wrong thing. And then I sat down and thought about it and I went back through the history. And I decided my answer to that is, Well, if that's true, tell Dr. Frederick Kleiner, Dr. Linus Pauling, Doctor, Dr. Archie Callow, Chirinos, who was in Australia saving children's lives. They were dying. One and two children was dying after being vaccinated while they were ill, they were dying of sudden infant death syndrome. And he saved he it stopped this epidemic of one in two children dying, stopped by giving injections of synthetic vitamin C sodium ascorbate. Tell Robert Cathcart, who has treated what did I say, 15,000 or something like that. People tell the hundreds of doctors and practitioners who are reversing disease with artificial vitamin C every day, including myself, the thousands of infants who are now growing up having survived whooping cough without lots of drama, without drugs, and now they're going to have upwards of 30 years of immunity because they had the natural disease in 1936. Even doctors were describing that scurvy cases actually didn't respond to food sometimes and that they only responded to intramuscular injections. So there's another study here showing these guinea pigs that were kept alive for one year on a flavonoid free diet with synthetic ascorbate. So the proof is in the history. You know, it's obviously it's good to eat food. Like I keep saying, get the and it's very good. But when you're using vitamin C this way, you're using it as a drug. And to me, it's a better drug than an antibiotic or than any other drug that starts with anti that's going to suppress a symptom because this actually gets your body up and running the way it's supposed to be. And so l ascorbic acid in the form of sodium ascorbate ingested or injected does cure scurvy. And with that, I will stop. Thank you.

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